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- ZORVOLEX diclofenac capsules are a nonsteroidal anti-inflammatory drug, available as hard gelatin capsules of 18 mg and 35 mg for oral administration.
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Zorvolex, produced by Iroko Pharmaceuticals, LLC, was previously approved for the treatment of mild to moderate acute pain in adults. The approval for osteoarthritis pain is an additional indication. The submicron particles are about 20 times smaller than the size found in the other diclofenac medications.
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The fixed combination of orphenadrine 35mg, mg, caffeine 65mg and diclofenac sodium 50mg aims to provide patients with anti-inflammatory, analgesic and myorelaxant action with adequate safety and tolerability profile. Diclofenac is a nonsteroidal anti-inflammatory with analgesic, anti-inflammatory and antipyretic action and is effective in the treatment of a variety of acute and chronic inflammatory and painful conditions. Its anti-inflammatory effect occurs by inhibiting the synthesis of prostaglandins by inhibiting COX-1 and COX-2 in an equipotent manner.
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