Common side effects include sleepiness, constipation, weight gain, and dry mouth. Quetiapine was developed in and approved for medical use in the United States in Quetiapine is primarily used to treat schizophrenia or bipolar disorder. In a comparison of 15 antipsychotics in effectiveness in treating schizophrenia, quetiapine demonstrated standard effectiveness. It is debatable whether, as a class, typical or atypical antipsychotics are more effective.

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Quetiapine is an atypical antipsychotic approved for the treatment of patients with psychotic disorders. Since approvement several case reports about intoxication with quetiapine were linked mainly with tachycardia, -prolongation, somnolence, and hyperglycemia. Symptoms associated with intoxication were coma without arterial hypotension, persistent tachycardia, hyperglycemia, and transient hypothyreoidism. Management consisted of intubation for airway protection, gastric lavage, the use of activated charcoal, i. Despite the extremely high dose of quetiapine, the patient recovered completely without residual symptoms. Quetiapine is indicated and approved for the treatment of psychotic disorders in adults by the U. Food and Drug Administration. After oral administration the drug is eliminated with a mean terminal half-life of approximately 7 hours.

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White, oval approx. Different dosing schedules exist for each indication. The total daily dose for the first 4 days of therapy is 50 mg day 1, mg day 2, mg day 3 and mg day 4. From day 4 onwards, the dose should be titrated to the usual effective dose range of to mg per day. Depending on the clinical response and tolerability of the individual patient, the https://medical-dictionary.thefreedictionary.com dose may be adjusted within the range of to mg per day.

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