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Risperidone Risperdal is a mixed serotonin-dopamine antagonist labeled to treat schizophrenia and mania associated with bipolar I disorder in adults. It was recently approved for the treatment of irritability associated with autistic disorder in children five to 17 years of age. Off-label uses include treatment of other symptoms of autistic disorder, including aggression, self-injurious behavior, hyperactivity, and inattention. Extrapyramidal symptoms e. Food and Drug Administration pregnancy category C. Most patients 50 to 75 percent will experience fatigue or drowsiness with risperidone.

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