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Reminyl XL is indicated for the symptomatic treatment of mild to moderately severe dementia of the Alzheimer type. The tolerance and dosing of galantamine should be reassessed on a regular basis, preferably within 3 months after start of treatment. Maintenance treatment can be continued for as long as therapeutic benefit is favourable and the patient tolerates treatment with galantamine. Discontinuation of galantamine should be considered when evidence of a therapeutic effect is no longer present or if the patient does not tolerate treatment. There is no rebound effect after abrupt discontinuation of treatment e.
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Rahel (taken for 3 to 7 years) 01.04.2019
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Galantamine hydrobromide is a white to almost white powder and is sparingly soluble in water. Inactive ingredients include diethyl phthalate, ethylcellulose, gelatin, hypromellose, polyethylene glycol, sugar spheres sucrose and starch, and titanium dioxide. The 16 mg capsule also contains red ferric oxide.
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Alzheimer's disease is characterized by the development of senile plaques and neurofibrillary tangles, which are associated with neuronal destruction, particularly in cholinergic neurons. Drugs that inhibit the degradation of acetylcholine within synapses are the mainstay of therapy. Donepezil, rivastigmine, and galantamine are safe but have potentially troublesome cholinergic side effects, including nausea, anorexia, diarrhea, vomiting, and weight loss.
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There may, sometimes, be other side-effects that are not listed above. In April, MHRA released advice that domperidone should no longer be prescribed to treat conditions such as gastro-oesophageal reflux and heartburn. However, medicines can be used in different ways for different patients.
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