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A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid see mesalamine released in the colon. From Martindale, The Extra Pharmacopoeia, 30th ed, p A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Sulfasalazine is an anti-inflammatory indicated for the treatment of ulcerative colitis and rheumatoid arthritis.
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Oral prodrug; metabolized by intestinal bacteria to sulfapyridine and 5-aminosalicylate 5-ASA, also known as mesalamine Used to treat ulcerative colitis, rheumatoid arthritis, and juvenille idiopathic arthritis JIA The sulfapyridine component is particularly associated with adverse reactions vs. Initially, 1 gram PO every 6 to 8 hours.
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