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For both hypertension and angina the usual initial dose is 5 mg amlodipine once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response. In hypertensive patients, Amlodipine has been used in combination with a thiazide diuretic, Alpha blocker, beta blockers, or an angiotensin-converting enzyme inhibitors, No dose adjustment of Amlodipine is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors. The recommended antihypertensive oral dose in pediatric patients ages years is 2. Doses in excess of 5 mg daily have not been studied in pediatric patients see section 5. The 2. Amlodipine, used at similar doses in elderly or younger patients, is equally well tolerated.
Amlodipine is used alone or in combination with other classes of antihypertensive agents in the management of hypertension. Amlodipine in fixed combination with atorvastatin Caduet is used in patients for whom treatment with both amlodipine and atorvastatin is appropriate.
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