Inhibits transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction. Therapeutic Effect s : Systemic vasodilation resulting in decreased BP. Coronary vasodilation resulting in decreased frequency and severity of attacks of angina. Reduction of ventricular rate in atrial fibrillation or flutter. CNS: abnormal dreams, anxiety, confusion, dizziness, drowsiness, headache, nervousness, psychiatric disturbances, weakness. Underline indicate most frequent. Lab Test Considerations: Total serum calcium concentrations are not affected by calcium channel blockers.
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The chemical structure is. Diltiazem hydrochloride is a serious to off-white crystalline powder with a bitter aftertaste.
- Diltiazem is a member of the calcium channel blocking agents drug class and is commonly used for Angina Pectoris Prophylaxis, Atrial Fibrillation, Atrial Flutter, and others.
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