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Etodolac works by reducing the levels of hormones that cause inflammation and pain in the body. Etodolac may also be used for other purposes.
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Long-term administration of NSAIDs may result in renal papillary necrosis and other renal injury; patients at greatest risk include elderly individuals; those with impaired renal function, hypovolemia, heart failure, liver dysfunction, or salt depletion; and those taking diuretics, angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockers. May inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects may contribute to anti-inflammatory activity.
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Etodolac is a member of the pyranocarboxylic acid group of non-steroidal anti-inflammatory drugs NSAIDs. Each capsule contains etodolac for oral administration. It has a pKa of 4.
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Meclizine can cause drowsiness. Alcohol, sedatives and tranquilizers may increase drowsiness.
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Even mixing them with grapefruit juice can worsen side effects. These are issues your doctor needs to talk to you about during an office visit before he prescribes the medicine.
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