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Comparative antibacterial efficacies of erythromycin, clarithromycin, and azithromycin were examined against Streptococcus pneumoniae and Haemophilus influenzae, with amoxicillin-clavulanate used as the active control. Against H. In experimental respiratory tract infections in rats, clarithromycin equivalent to mg twice daily b. Overall, amoxicillin-clavulanate was effective in vitro and in vivo. Clarithromycin and erythromycin were ineffective in https://www.ohiohealth.com vitro and in vivo against H. These results may have clinical implications for the utility of macrolides in the empiric therapy of respiratory tract infections.
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This leaflet is about the use of the antibiotic erythromycin for the treatment of bacterial infections. If your child has ever had a reaction to any medicine, check with your doctor that your child can have erythromycin, before giving it.
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The penetration of erythromycin was studied in cases of secretory otitis media. The concentration of erythromycin in the middle ear effusions reached the plasma level 1. The plateau levels were https://www.wrcbtv.com maintained during the steady state. Elimination was slow; 14 hours after the last dose of a ten-day treatment, the concentration of erythromycin in the middle ear effusions was still as high as 0. The concentration of erythromycin in the middle ear effusions surpassed the MICs of most respiratory pathogens. Erythromycin can thus be regarded as a suitable drug in the treatment of otitis media.
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