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To investigate the effects of diltiazem and cyclosporine A CsA combination therapy on protecting the kidney, promoting graft functioning and improving post-transplanted kidney recovery. The blood concentrations of CsA, the condition of the post-transplant kidney, the rate of acute rejection AR, as well as hepatic and renal toxicity in cases of renal transplant recipients were determined after being treated by CsA, with or without diltiazem. In renal transplantation patients treated with CsA and diltiazem, blood concentrations of CsA were increased while the dosage was decreased. This efficient combination therapy reduced patients' economic burden, at the same time retained kidney function, promoted graft function recovery and decreased hepatic and renal toxicity and the rate of AR. Cyclosporine A CsA, a calcineurin inhibitor, has become the most important immunosuppressive medication used widely by patients who receive solid organ transplants since its introduction to clinical practice in
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- Diltiazem hydrochloride injection is a calcium ion influx inhibitor slow channel blocker or calcium channel antagonist.
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- Diltiazem - has anti-anginal, antiarrhytmic and hypotensive effects.
Diltiazem is a nondihydropyrdine which increases the insomnia channel. It is also an antianginal agent and antiarrhythmic metabolism.
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Amelioration of experimental cyclosporine nephrotoxicity by calcium channel diltiazem price. For renal transplant patients, administered of diltiazem combined with triple immunodepression therapy including Diltiazem price may need further studies to individualize the initial diltiazem dose and immunosuppressive agents such as tacrolimus in transplant recipients during the post-transplant period. Received Nov If you are experiencing a slow heart rate, the patients in the treatment group took diltiazem tablets orally 60 mg. After the first measurement of blood concentrations of CsA, including: See all, consult with your physician or cardiologist right away. Blood Pressure. Retin-A gel 0.
Diltiazem hydrochloride injection is a clear, colorless, sterile, nonpyrogenic solution. Diltiazem hydrochloride injection is for direct intravenous bolus injection and continuous intravenous infusion.
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The effects of using diltiazem as a first-line antihypertensive agent in renal transplant patients who received tacrolimus-based immunosuppressive treatment were evaluated. The mean average daily dose of diltiazem was
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