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- But since the original studies were conducted only for 12 to 14 weeks, the long-term effectiveness of the drug could not be determined.
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- The majority of studies examining use of pseudoephedrine in pregnancy did not find an association with increased risk of congenital anomalies; a few case-control studies conducted reported potential associations with isolated congenital disorders; however, methodological limitations of these studies made the interpretation of results unreliable.
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