Subjects will undertake a 1-week screening period to provide baseline data and for assessment of eligibility. Study treatment will be applied in and around the anus, three times daily, for up to 8 weeks. Concomitant laxatives and stool softeners will be permitted, as needed, during the entire study period screening and treatment to ensure that constipation or passage of hard stools does not confound evaluation or improvement of the condition. Fibre supplements will be allowed but should be continued at the baseline level. A record of the number of times the subject has defaecated, laxative and analgesic usage will also be made as well as the number of applications of study treatment, any changes to concurrent medications and any Adverse Events AEs. Subjects may receive permitted medications for pain per Entry Criteria, but these should remain stable, where possible, up to the Week 8 Visit.
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It's also sometimes used to treat abnormal heart rhythms arrhythmia. Diltiazem works by relaxing blood vessels and increasing the supply of blood and oxygen to the heart. This type of medication is known as a calcium-channel blocker. Your doctor will likely start you on a low dose of diltiazem and then gradually increase your dose. Your blood pressure and pulse will be checked regularly while taking diltiazem to determine your response to the drug. You should also tell your doctor if you plan to have any type of surgery, including dental surgery.
Before taking diltiazem, tell your doctor if you have kidney disease, liver disease, or congestive heart failure. Diltiazem may be only part of a complete program of treatment that also includes diet, exercise, and other medications. If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. It works by relaxing the muscles of your heart and blood vessels. Diltiazem is used to treat hypertension high blood pressure, angina chest pain, and certain heart rhythm disorders.
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Directions Take your medicine as directed. In a few reported cases, excessive bradycardia. Close cheap diltiazem hydrochloride of blood pressure is recommended until the full effects of the combination therapy are known! Specific dosage adjustment recommendations are available for the Cheap diltiazem hydrochloride product for patients who have taken diltiazem in the past 14 days or require concurrent use: for prophylaxis of gout flares, fentanyl plasma concentrations will decrease resulting in reduced efficacy of the opioid and potential withdrawal syndrome in a patient who has developed physical dependence to fentanyl? Meloxicam: Moderate If nonsteroidal anti-inflammatory drugs NSAIDs and an antihypertensive drug are concurrently used, carefully monitor the patient for signs and symptoms of renal insufficiency and blood pressure control.
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Excipient s with known effect: Each tablet contains NOT indicated for acute attacks of angina. The usual dose is one tablet 60mg three times daily.
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The chemical structure is. Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste.
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Diltiazem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.
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