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Contains amoxicillin and clavulanic acid; clavulanic acid is a beta-lactamase inhibitor that reestablishes amoxicillin's activity against beta-lactamase-producing bacteria; drug combination has good activity against beta-lactamase producing H. Treat for 10 days. The every 12 hour regimen is preferred in children because it causes less diarrhea than every 8 hour regimens. The FDA-approved labeling recommends a treatment duration of 10 days. The American Academy of Pediatrics AAP recommends a day course for any child with severe disease and for all patients younger than 2 years of age, regardless of severity. For children 2 to 5 years with mild to moderate disease, a 7-day course is acceptable.
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