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Celebrex is indicated in adults for the symptomatic relief in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. The decision to prescribe a selective cyclooxygenase-2 COX-2 inhibitor should be based on an assessment of the individual patient's overall risks see sections 4. As the cardiovascular CV risks of celecoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The usual recommended daily dose is mg taken once daily or in two divided doses. In some patients, with insufficient relief from symptoms, an increased dose of mg twice daily may increase efficacy.

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Gastrointestinal Bleeding, Ulceration, and Perforation. For the management of the signs and symptoms of OA. For OA, the dosage is mg per day administered as a single dose or as mg twice daily. For JRA, the dosage for pediatric patients age 2 years and older is based on weight. If no effect is observed after 6 weeks, https://intermountainhealthcare.org a trial of mg daily may be worthwhile.

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