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Celecoxib is a selective cyclo-oxygenase-2 COX-2 inhibitor that has been fully subsidised without restriction, since 1 June, Celecoxib may be considered for the treatment of patients with acute pain, arthritic conditions or primary dysmenorrhoea as an alternative to the non-selective non-steroidal anti-inflammatory drugs NSAIDs, e. A significant benefit of celecoxib is that it is associated https://www.youtube.com with less risk of gastrointestinal bleeding compared to non-selective NSAIDs. Use of celecoxib is associated with an increase in cardiovascular risk, but this risk is similar to that associated with non-selective NSAIDs. Celecoxib capsules and mg have been fully subsidised in New Zealand, without restriction, since June 1, Celecoxib is generally considered to be equally effective as naproxen, ibuprofen and diclofenac in reducing pain and inflammation. The inhibition of COX-2 prevents the production of the prostaglandins that mediate pain, inflammation and fever. However, as the selectivity for COX-2 inhibition increases, so does the risk of cardiovascular events. However, as celecoxib does possess some degree of COX-1 inhibition at higher doses, the adverse effects associated with celecoxib are broadly similar to those of the non-selective NSAIDs, although their frequency may differ.
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