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Effexor - antidepressant. Active ingredient - venlafaxine and its main metabolite O-desmetilvenlafaxine which are strong inhibitors of the return serotonin reuptake and noradrenaline and weak inhibitors of the return capture of a dopamine. It is considered that the mechanism of antidepressive action is connected with ability of drug to strengthen transfer of nervous impulses in CNS.
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The mechanism of antidepressant action is associated with the ability of the drug to enhance the activity of neurotransmitters during the transmission of nerve impulses in the central nervous system CNS. Venlafaxine and EFA equally effectively affect the reuptake of the above-mentioned neurotransmitters, and they do not have affinity studied in vitro with cholinergic muscarinic, histamine H 1 alpha 1 -adrenergic, opioid and benzodiazepine receptors, do not inhibit the activity of monoamine oxidase MAO.
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