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- Using other drugs that treat organ transplant rejection along with this drug may increase these tendencies.
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- Cyclosporine Neoral, Sandimmune, Gengraf is a potent immunosuppressant drug used in treatment for rheumatoid arthritis, lupus, and other autoimmune diseases.
- Classification: Immunosuppressant Agent.
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Treatment of transplant cellular rejection in patients previously receiving other immunosuppressive agents. Treatment of sight-threatening intermediate or posterior uveitis of non-infectious aetiology in patients in whom conventional therapy has failed or caused unacceptable side effects. Steroid-dependent and steroid-resistant nephrotic syndrome, due to primary glomerular diseases such as minimal change nephropathy, focal and segmental glomerulosclerosis, or membranous glomerulonephritis. Neoral can be used to induce and maintain remissions. It can also be used to maintain steroid-induced remission, allowing withdrawal of steroids.
Increased susceptibility to infection and the possible development of lymphoma and other neoplasms may result from the increase in the degree of immunosuppression in transplant patients. Dose adjustments should be made in transplant patients to minimize possible organ rejection due to low concentrations. The risk increases with increasing dose and duration of cyclosporine therapy.
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