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The authors of this study suggested that this increase is unlikely to be of clinical concern. Escitalopram can also prolong the QT interval and hence it is not recommended in patients that are concurrently on other medications that also have the ability to prolong the QT interval. These drugs include antiarrhythmics, antipsychotics, tricyclic antidepressants, some antihistamines astemizole, mizolastine and some antiretrovirals ritonavir, saquinavir, lopinavir.
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