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Olmesartan Benicar is an angiotensin-II receptor blocker ARB labeled for the treatment of hypertension as monotherapy or in combination with other antihypertensive agents. Olmesartan blocks the binding of angiotensin II, a potent vasoconstrictor, to angiotensin type 1 AT 1 receptors located in vascular smooth muscle.
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Olmesartan medoxomil, a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract. Olmesartan is a selective AT 1 subtype angiotensin II receptor antagonist. Olmesartan medoxomil is a white to light yellowish-white powder or crystalline powder with a molecular weight of
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