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- Potassium-sparing diuretic; used for edema, ascites, HTN, hypokalemia, acne vulgaris, polycystic ovary syndrome, female hirsutism, and to diagnose primary hyperaldosteronism; also improves survival and NYHA functional class, and reduces hospitalizations in NYHA Class IV heart failure.
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- Excretion: The metabolites are excreted primarily in the urine and secondarily in bile.
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The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. Aldactone 25 mg Tablet. Manufactured by Rpg Life Sciences Ltd. Contains Spironolactone.
Children should only be treated under guidance of a paediatric specialist. There is limited paediatric data available see sections 5.
Hildegard (taken for 3 to 7 years) 04.05.2016
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Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. Label Off label uses of spironolactone involving its antiandrogenic activity include hirsutism, female pattern hair loss, and adult acne vulgaris.
Albert (taken for 1 to 7 years) 18.03.2016
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Spironolactone is a potassium-sparing diuretic. The drug may also be used in combination with other medications to treat precocious early puberty and myasthenia gravis, a neuromuscular disease. Though spironolactone has been around for over 25 years, the FDA is still updating the drug's safety labeling.
Jonas (taken for 3 to 6 years) 13.01.2017
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Lina (taken for 1 to 7 years) 14.08.2016
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