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If you're going to take isotretinoin, prepare to get really familiar with the iPledge program. This program was put in place to prevent birth defects caused by isotretinoin. You'll need to enroll in iPledge to get your prescription; it's a requirement for everyone who is prescribed isotretinoin medications like Absorica, Amnesteem, Claravis, and Sotret.
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Accutane is dispensed only under the rules of iPledge, a government regulated prescription program. Due to the risks associated with pregnancy, the rules for females are particularly strict. Our society increasingly relies on family and friends as caregivers for those who can no longer care for themselves.
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The continued availability of ISO has at times been challenged due to its teratogenicity warranting further emphasis on continued patient education and the introduction of a structured, traceable, and mandated risk-management program iPLEDGE. Several million patients, including a subset of children, have been treated with ISO. Importantly, ISO remains the only therapy for acne that is capable of inducing remission after an adequate course of therapy is completed, with prolonged remissions occurring with reasonable certainty in most patients.
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